Slide 1: Optimizing PEEP in COVID-19 ARDS. Slide 2: The Global Impact of COVID-19 ARDS. Slide 3: Mechanical Ventilation: A Double-Edged Sword. Slide 4: The PEEP Titration Conundrum in COVID-19 ARDS. Slide 5: Study Objective: A Novel PEEP Titration Protocol. Slide 6: Study Design & Setting. Slide 7: Patient Cohort: Focus on Obese ARDS Patients. Slide 8: Intervention: Transpulmonary Pressure-Guided PEEP Trial. Slide 9: Key Variables of Interest. Slide 10: Conclusion & Future Directions